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Table 5 Comparison of endocrine levels between women with and without anxiety and depression (n = 1234)

From: Factors associated with anxiety and depression in perimenopausal women with abnormal uterine bleeding: A retrospective cohort study

Endocrine Marker

Anxiety & Depression Group (n = 418)

Non-Anxiety & Non-Depression Group (n = 416)

P-value

Estradiol (pg/mL), Mean ± SD

58.7 ± 22.0

67.5 ± 23.5

< 0.001***

FSH (mIU/mL), Mean ± SD

27.9 ± 8.4

22.5 ± 8.6

< 0.001***

LH (mIU/mL), Mean ± SD

23.5 ± 6.9

19.8 ± 6.7

< 0.001***

Cortisol (µg/dL), Mean ± SD

15.8 ± 5.2

13.1 ± 5.4

< 0.001***

Prolactin (ng/mL), Mean ± SD

19.6 ± 6.1

17.8 ± 6.0

0.002**

Testosterone (ng/dL), Mean ± SD

0.52 ± 0.15

0.49 ± 0.13

0.034*

TSH (mIU/L), Mean ± SD

2.71 ± 1.14

2.41 ± 1.10

0.012*

  1. Note: Data are presented as mean ± standard deviation. P-values were calculated using t-tests to compare the mean endocrine levels between the anxiety & depression group and the non-anxiety & non-depression group. *Significance levels: *P < 0.05, **P < 0.01, ***P < 0.001