Table 4 Univariate and multivariate logistic regression analysis for factors associated with depression in perimenopausal women with abnormal uterine bleeding (n = 1234)
Variable | Univariate OR (95% CI) | P-value | Multivariate OR (95% CI) | P-value |
|---|---|---|---|---|
Age (years) | 1.04 (0.99–1.08) | 0.085 | 1.03 (0.98–1.07) | 0.109 |
BMI (kg/m²) | 1.08 (1.03–1.13) | 0.027* | 1.07 (1.02–1.12) | 0.033* |
Duration of Abnormal Uterine Bleeding (months) | 1.12 (1.05–1.18) | 0.002** | 1.09 (1.03–1.15) | 0.005** |
Marital Status (Single/Divorced/Widowed vs. Married) | 1.62 (1.18–2.24) | 0.007** | 1.49 (1.06–2.09) | 0.019* |
Education Level (Primary/Secondary vs. College/University) | 1.84 (1.45–2.33) | < 0.001*** | 1.66 (1.28–2.17) | < 0.001*** |
Smoking History (Yes vs. No) | 2.94 (1.83–4.72) | < 0.001*** | 2.72 (1.69–4.40) | < 0.001*** |
Exercise Regularly (≥ 3 times/week) (Yes vs. No) | 0.59 (0.45–0.78) | < 0.001*** | 0.68 (0.52–0.89) | 0.006** |
Psychiatric History (Yes vs. No) | 3.02 (2.14–4.26) | < 0.001*** | 2.67 (1.88–3.78) | < 0.001*** |
Estradiol (pg/mL) | 0.96 (0.94–0.98) | < 0.001*** | 0.97 (0.95–0.99) | 0.003** |
FSH (mIU/mL) | 1.05 (1.03–1.08) | < 0.001*** | 1.04 (1.02–1.07) | < 0.001*** |
LH (mIU/mL) | 1.03 (1.01–1.06) | 0.004** | 1.02 (1.00-1.05) | 0.012* |
Cortisol (µg/dL) | 1.11 (1.06–1.16) | < 0.001*** | 1.09 (1.04–1.15) | 0.002** |
Sleep Quality (PSQI Score) | 1.32 (1.25–1.39) | < 0.001*** | 1.29 (1.22–1.36) | < 0.001*** |