Table 1 Baseline characteristics of perimenopausal women with abnormal uterine bleeding (n = 1234)
Characteristic | Total (n = 1234) | Anxiety Group (n = 652) | Non-Anxiety Group (n = 582) | P-value |
|---|---|---|---|---|
Age (years), Mean ± SD | 48.7 ± 3.5 | 48.9 ± 3.4 | 48.5 ± 3.6 | 0.182 |
BMI (kg/m²), Mean ± SD | 25.8 ± 4.1 | 26.1 ± 4.2 | 25.5 ± 3.9 | 0.045* |
Duration of Abnormal Uterine Bleeding (months), Median (IQR) | 8 (3–12) | 10 (5–13) | 7 (3–11) | 0.003** |
Marital Status, n (%) | ||||
- Married | 954 (77.3) | 482 (73.9) | 472 (81.1) | 0.008** |
- Single/Divorced/Widowed | 280 (22.7) | 170 (26.1) | 110 (18.9) | |
Education Level, n (%) | ||||
- Primary/Secondary | 645 (52.3) | 380 (58.3) | 265 (45.5) | < 0.001*** |
- College/University | 589 (47.7) | 272 (41.7) | 317 (54.5) | |
Smoking History, n (%) | 98 (7.9) | 74 (11.4) | 24 (4.1) | < 0.001*** |
Alcohol Use, n (%) | 147 (11.9) | 89 (13.7) | 58 (10.0) | 0.052 |
Exercise Regularly (≥ 3 times/week), n (%) | 546 (44.3) | 232 (35.6) | 314 (53.9) | < 0.001*** |
Comorbidities, n (%) | ||||
- Hypertension | 398 (32.2) | 220 (33.7) | 178 (30.6) | 0.253 |
- Diabetes | 148 (12.0) | 89 (13.6) | 59 (10.1) | 0.052 |
Psychiatric History, n (%) | 256 (20.7) | 183 (28.1) | 73 (12.5) | < 0.001*** |
Endocrine Levels, Mean ± SD | ||||
- Estradiol (pg/mL) | 62.5 ± 22.4 | 60.2 ± 21.8 | 64.9 ± 23.0 | 0.012* |
- FSH (mIU/mL) | 25.6 ± 8.9 | 27.4 ± 8.6 | 23.7 ± 8.8 | < 0.001*** |
- LH (mIU/mL) | 21.8 ± 6.7 | 22.9 ± 6.5 | 20.7 ± 6.8 | < 0.001*** |
- Cortisol (µg/dL) | 14.2 ± 5.3 | 15.6 ± 5.1 | 12.7 ± 5.5 | < 0.001*** |
- Prolactin (ng/mL) | 18.9 ± 6.3 | 19.5 ± 6.5 | 18.2 ± 6.0 | 0.002** |
Sleep Quality (PSQI Score), Median (IQR) | 7 (5–10) | 9 (6–12) | 6 (4–8) | < 0.001*** |