Table 4 Comparison of indicators in different MoCA score groups

Age[y, (P25, P75)]

61.5(52,64)

73(63,80)^a

70(62,76)^a

62(56,74)^bc

62(56,65)^bc

24.3821

Sex(male/female)

4(40)/6(60)

21(48.84)/22(51.16)

24(61.54)/15(38.46)

30(63.83)/17(36.17)

20(60.61)/13(39.39)

3.5748

Education level (y)(≥12)

6(60)

41(95.35)a

37(94.87)a

40(85.11)

20(60.61)bcd

24.9557

Hypertension

3(30)

31(72.09)

26(66.67)

35(74.47)

19(57.58)

9.0705

Coronary heart disease

4(40)

16(37.21)

12(30.77)

22(46.81)

12(36.36)

2.4599

Diabetes mellitus

0(0)

12(27.91)

7(17.95)

11(23.4)

4(12.12)

5.9498

Smoking

2(20)

21(48.84)

16(41.03)

27(57.45)

14(42.42)

5.8712

Drinking

4(40)

17(39.53)

15(38.46)

23(48.94)

11(33.33)

2.1702

Stroke or cerebral infarction

3(30)

25(58.14)

23(58.97)

24(51.06)

12(36.36)

6.4494

0.1680

Hypohepatia

3(30)

4(9.3)

2(5.13)

3(6.38)

0(0)

--

Renal dysfunction

2(20)

5(11.63)

2(5.13)

2(4.26)

4(12.12)

--

Thyroid dysfunction

0(0)

4(9.3)

4(10.26)

1(2.13)

3(9.09)

--

Family history of dementia

1(10)

2(4.65)

5(12.82)

5(10.64)

6(18.18)

--

Other family history

8(80)

13(30.23)a

19(48.72)

25(53.19)b

18(54.55)b

10.6144

Hight [ cm, (P25, P75)]

163.5(160,175)

165(158,170)

166(160–170)

165(160–170)

169(160–175)

6.6330

Weight(kg)

60(58–75)

60(54–70)

69.5(60–71)

70(60–75)

70(60–75)

9.1741

SBP [mmHg, (P25, P75)]

128(120,140)

140(121,150)

147(140,160)^ab

142(130,160)^a

140(130,140)^c

11.0435

DBP [mmHg, (P25, P75)]

80(78,90)

85(80,90)

90(80,91)

83(80,96)

80(80,90)

3.3197

Glu(mmol/L)

5.63(5.23–5.78)

5.48(4.95–7.05)

5.35(4.93–6.57)

6.43(5.08–7.93)

5.67(5.14–6.4)

4.4125

TG(mmol/L)

1.34(0.93–1.8)

1.2(0.98–2.05)

1.14(0.94–1.94)

1.59(1.07–2.13)

1.4(1.14–2.16)

2.8574

T-CH(mmol/L)

4.38(3.74–5.16)

4.95(3.92–5.39)

4.39(3.64–5.09)

4.42(4.07–4.85)

4.75(4.25–5.34)

4.3797

LDL-C(mmol/L)

2.46(1.84–3.22)

3.07(2.48–3.6)

2.6(2.21–3.65)

2.93(2.56–3.26)

2.89(2.58–3.36)

4.6499

HDL-C(mmol/L)

1.18(0.87–1.66)

1.1(0.95–1.33)

1.1(0.88–1.38)

1.16(0.94–1.36)

1.16(1.04–1.38)

2.4658

BUN(mmol/L)

5.01(4.21–5.59)

5.81(4.73–6.89)

5.73(4.76–6.97)

6.21(4.95–7.08)

5.01(4.34–7.15)

8.0485

Cr(umol/L)

73.3(55.9–84.4)

80(66.8–96.9)

84.4(69-96.4)

82.3(67.9–96)

73.6(64.7–89.1)

3.8055

ALT(U/L)

19.5(16–35)

12(8–20)^a

18(12–23)^b

19(13–26)^b

17(14–25)^b

13.1867

AST(U/L)

20.5(15–30)

13(11–17)^a

17(13–22)^b

18(13–23)^b

17(13–22)^b

13.1339

WBC (109/L)

7.15(4.1-8)

7(6.2–8.2)

7.4(5.6–8.2)

7.4(6.1–8.8)

6.7(5.8–8.2)

2.2924

CRP(mg/L)

1.51(0.67–1.59)

2.28(1.39–4.95)

1.83(0.65–6.35)

2.35(0.94–4.85)

1.55(0.83–2.42)

7.1093

ADMA concentration(umol/L)

43.65(36.17–53.74)

56.76(47.65–65.74)^a

58.49(42.94–66.13)^a

55.51(46.13–60.63)

47.9(37.93–57.63)^bc

10.1315

GFR(ml/min)

52.61(24.56–84.16)

58.23(37.75–82.17)

75.27(35.39–96.12)

73.49(37.56-100.39)

62.75(37.98–97.35)

3.3183

Ccr(ml/min)

83.26 ± 22.28

61.72 ± 22.7^a

68.46 ± 21.15

74.26 ± 21.7^b

83.32 ± 26.25^bc

5.1816

MMSE score(P25, P75)

29.5(29,30)

18(15,22)^a

23(21,25)^ab

25(24,27)^abc

26(26,27)^abcd

103.030

MoCA score(P25, P75)

26(25,28)

10(9,12)^a

15(14,16)^ab

19(18,20)^abc

23(23,24)^abcd

161.500

Adjustive MMSE

30(29–30)

19(16–23)^a

24(22–26)^ab

26(25–27)^abc

27(26–28)^abcd

96.3713

(Based on years of schooling)

26.5(26–29)

11(10–13)^a

16(15–17)^ab

20(19–21)^abc

24(23–25)^abcd

162.270