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Table 2 Areas under ROC curves for MCI and AD groups relative to healthy controls

From: Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer’s disease

Composite

Clinical group

Sensitivity (95% CI) score < 90

Specificity (95% CI) score < 90

Area under ROC curve (95% CIs)

Standard error

p

Psychomotor/attention

AD

52.9% (38.5%, 67.1%)

85.7% (82.8%, 88.3%)

0.73 (0.64, 0.82)

0.05

< 0.0001

 

MCI

41.1% (31.7%, 51.1%)

85.7% (82.8%, 88.3%)

0.67 (0.61, 0.73)

0.03

< 0.0001

  

Score < 90

Score < 90

   

Learning/working memory

AD

100.0% (91.5%, 100.0%)

84.7% (81.7%, 87.4%)

0.99 (0.98, 1.00)

0.01

< 0.0001

 

MCI

80.4% (71.6%, 87.4%)

84.7% (81.7%, 87.4%)

0.91 (0.87, 0.94)

0.02

< 0.0001

  1. Note: ROC = receiver operating characteristic; MCI = mild cognitive impairment; AD = Alzheimer’s disease; Attention/psychomotor composite = average of the standardized Detection and Identification scores; Learning/working memory composite = average of the standardized One Card Learning and One Back scores; MMSE = Mini Mental State Examination.
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BMC Psychology

ISSN: 2050-7283

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